2 Results for "

20-Carboxy-Leukotriene B4

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "20-Carboxy-Leukotriene B4" in MCE Product Catalog:

20-Carboxy-Leukotriene B4
20-Carboxy-Leukotriene B4
0 Images
Cat. No.: HY-113483
CAS No.: 80434-82-8
Purity:  ≥98.0%
Synonyms: 20-COOH LTB4
Target:  

Drug Metabolite Leukotriene Receptor

Research Areas:  

Metabolic Disease

20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis) .
loading...
    loading...
View All Sizes
Semaglutide-d8 tetraTFA
Semaglutide-d8 tetraTFA
0 Images
Cat. No.: HY-114118S1
Target:  

Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

Research Areas:  

Neurological Disease Metabolic Disease Cancer

Semaglutide-d8 tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
loading...
    loading...
View All Sizes
Assay Types