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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
8-Oxoguanine
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "8-Oxoguanine" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1). SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection .
3
3 Cited Publications
Target:
Research Areas:
OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1 .
3
3 Cited Publications
Cat. No.: HY-P70968
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: OGG1; DNA-(Apurinic Or Apyrimidinic Site) Lyase; 8-Oxoguanine DNA Glycosylase; DNA-Apurinic Or Apyrimidinic Site Lyase; OGH1; OGG1 Type 1e; MUTM; OGG1 Type 1d; N-Glycosylase/DNA Lyase; OGG1 Type 1g; HOGG1; OGG1 Type 1h; HMMH; OGG1 Type 1f; 8-Hydroxyguanin
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72338
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OGG1; DNA-(Apurinic Or Apyrimidinic Site) Lyase; 8-Oxoguanine DNA Glycosylase; DNA-Apurinic Or Apyrimidinic Site Lyase; OGH1; OGG1 Type 1e; MUTM; OGG1 Type 1d; N-Glycosylase/DNA Lyase; OGG1 Type 1g; HOGG1; OGG1 Type 1h; HMMH; OGG1 Type 1f; 8-Hydroxyguanin
Species:
Human
Source:
E. coli
Category:
Natural Products Immune System Disorder Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-E72032
Target:
Research Areas:
8-Oxoguanine deaminase (EC 3.5.4.32) is a hydrolase that can convert 8-oxoguanine, H2O and H + into urate and NH4 +.
Cat. No.: HY-179014
Target:
Research Areas:
OGG1 activator-1 (Compound 30) is a selective 8-oxoguanine DNA glycosylase-1 (OGG1) activator with an AC50 value of 0.58 μM. OGG1 activator-1 does not activate nor inhibit the key downstream repair enzyme APE1, and shows > 150-fold selectivity for the activation effect on OGG1. OGG1 activator-1 exhibits extremely high metabolic stability and almost no cytotoxicity. OGG1 activator-1 can be used for the study of oxidative stress-related diseases (such as neurodegenerative diseases, fibrotic diseases, cancer, inflammation, etc.) .
Cat. No.: HY-113338A
CAS No.: 1246818-54-1
Synonyms: 8-Oxoguanine hydrochloride; 8-oxo-Gua hydrochloride
Target:
Research Areas:
8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine hydrochloride induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine hydrochloride is a marker of DNA oxidative damage .
Cat. No.: HY-P72338A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: OGG1; DNA-(Apurinic Or Apyrimidinic Site) Lyase; 8-Oxoguanine DNA Glycosylase; DNA-Apurinic Or Apyrimidinic Site Lyase; OGH1; OGG1 Type 1e; MUTM; OGG1 Type 1d; N-Glycosylase/DNA Lyase; OGG1 Type 1g; HOGG1; OGG1 Type 1h; HMMH; OGG1 Type 1f; 8-Hydroxyguanin
Species:
Human
Source:
E. coli
Cat. No.: HY-P74740
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUDT1; Methylated Purine Nucleoside Triphosphate Hydrolase; Prev. MTH1; 8-Oxo-7,8-Dihydrodeoxyguanosine Triphosphatase; 7,8-Dihydro-8-Oxoguanine Triphosphatase; Nucleoside Diphosphate-Linked Moiety X Motif 1; Nudix Motif 1; 8-Oxo-7,8-Dihydroguanosine Trip
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
