3 Results for "

9-HODE

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "9-HODE" in MCE Product Catalog:

Cat. No.: HY-113545A
CAS No.: 98524-19-7
Target:  

Drug Isomer

Research Areas:  

Metabolic Disease

(±)9-HODE is a racemate of 9-HODE. 9-HODE is a oxidized derivatives of Linoleic acid (HY-N0729) .
loading...
    loading...
Cat. No.: HY-123016A
CAS No.: 33783-76-5
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(±)9-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL.2 Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 9-HODE cholesteryl ester.
loading...
    loading...
Cat. No.: HY-184442
Target:  

G2A (GPR132)

Research Areas:  

Neurological Disease

GPR132 antagonist-2 is a G2A (GPR132) antagonist with an IC50 of 0.69 μM. GPR132 antagonist-2 exerts weak stabilizing effects on the bromodomain of BRD2 and exhibits selectivity for non-olfactory GPCRs. GPR132 antagonist-2 inhibits G2A activation, blocks downstream inositol monophosphate accumulation, reverses G2A-mediated TRPV1 sensitization, suppresses 9-HODE-mediated capsaicin-induced TRPV1 responses, and activates FPR3. GPR132 antagonist-2 can be used in studies related to neuropathic pain .
loading...
    loading...