1 Result for "

AL002

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AL002" in MCE Product Catalog:

Cat. No.: HY-P991220

Target:  

TREM receptor

Research Areas:  

Neurological Disease

AL002 is a humanized monoclonal IgG1 antibody and a blood-brain barrier-permeable TREM2 modulator. AL002 binds to TREM2 on the surface of microglia, promotes TREM2 clustering and the formation of the TREM2-DAP12 complex, activates the TREM2 signaling pathway and PI3K cascade, and induces TREM2 internalization and degradation. AL002 is applicable to research related to Alzheimer's disease .
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