1 Result for "

AMU302

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AMU302" in MCE Product Catalog:

Cat. No.: HY-157169
CAS No.: 1414455-21-2
Purity:  98.21%
Synonyms: AMU302
Target:  

Pim mTOR Akt PI3K

Research Areas:  

Cancer

IBL-302 (AMU302) is an orally available dual-signaling inhibitor of PIM and PI3K/AKT/mTOR with activity against breast cancer and neuroblastoma. IBL-302 demonstrated in vivo efficacy in a nude mouse xenograft model, inhibiting trastuzumab (HY-P9907) resistance challenges. IBL-302 also enhances the effects of common cytotoxic chemotherapy drugs cisplatin (HY-17394), doxorubicin (HY-15142A), and etoposide (HY-13629) .
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