3 Results for "

ARC-1905

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "ARC-1905" in MCE Product Catalog:

Cat. No.: HY-147080
CAS No.: 1491144-00-3
Purity:  98.53%
Synonyms: ARC1905
Target:  

Complement System

Research Areas:  

Others

Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system .
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Cat. No.: HY-153098
ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
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Cat. No.: HY-153098A
Purity:  94.13%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
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