1 Result for "

ASP 0367

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ASP 0367" in MCE Product Catalog:

Art. -Nr.: HY-134377
CAS. Nr.: 2095128-20-2
Reinheit:  98.08%
Synonyms: ASP0367; MA-0211
Target:  

PPAR

Forschungsgebiete:  

Metabolic Disease

Bocidelpar (ASP0367; MA-0211) is a selective, orally active PPARδ modulator. Bocidelpar activates the PPARδ downstream signaling pathway, upregulates the expression of target genes such as ABCA1 and ACAA2. Bocidelpar then promotes fatty acid oxidation (FAO) and mitochondrial biogenesis, and improves mitochondrial dysfunction. Bocidelpar can improve mitochondrial biogenesis and function in muscle cells. Bocidelpar is mainly used in the study of mitochondrial dysfunction diseases such as primary mitochondrial myopathy (PMM) and Duchenne muscular dystrophy (DMD) .
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