1 Result for "

AV457

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AV457" in MCE Product Catalog:

Cat. No.: HY-168884
CAS No.: 2713387-11-0
Target:  

mTOR

Research Areas:  

Metabolic Disease

AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT .
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