15 Results for "

Ames test

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Ames test" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0035
CAS No.: 57-68-1
Synonyms: Sulfadimidine; Sulfadimerazine
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Neurological Disease

Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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3
3 Cited Publications
Cat. No.: HY-B0035A
CAS No.: 1981-58-4
Synonyms: Sulfadimidine sodium; Sulfadimerazine sodium
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Neurological Disease

Sulfamethazine (Sulfadimidine) sodium is a brain-penetrant sulfonamide antibiotic. Sulfamethazine sodium inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine sodium can be used for research on bacterial infections .
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Cat. No.: HY-B0035S
CAS No.: 1020719-82-7
Synonyms: Sulfadimidine-d4; Sulfadimerazine-d4
Sulfamethazine-d4 (Sulfadimidine-d4) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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Cat. No.: HY-B0035S2
CAS No.: 77643-91-5
Synonyms: Sulfadimidine-13C6; Sulfadimerazine-13C6
Sulfamethazine- 13C6 is a 13C-labeled Sulfamethazine (HY-A0178). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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Cat. No.: HY-B0035B
CAS No.: 57-68-1
Synonyms: Sulfadimidine 100 µg/mL in acetonitrile; Sulfadimerazine 100 µg/mL in acetonitrile
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Sulfamethazine (Sulfadimidine) 100 µg/mL in acetonitrile is a brain-penetrant sulfonamide antibiotic. Sulfamethazine 100 µg/mL in acetonitrile inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine 100 µg/mL in acetonitrile can be used for research on bacterial infections .
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Cat. No.: HY-122817
CAS No.: 73226-73-0
Target:  

Antibiotic Parasite

Research Areas:  

Infection

FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice .
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Cat. No.: HY-B0035R
CAS No.: 57-68-1
Synonyms: Sulfadimidine (Standard); Sulfadimerazine (Standard)
Research Areas:  

Infection

Sulfamethazine (Standard) is the analytical standard of Sulfamethazine (HY-B0035). This product is intended for research and analytical applications. Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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Cat. No.: HY-N5054
CAS No.: 1277188-85-8
(R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains . And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato .
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Cat. No.: HY-W795264
CAS No.: 66508-32-5
Target:  

Parasite

Research Areas:  

Infection

FR900098 is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 has no effect on bone marrow red blood cells in NMRI mice .
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Cat. No.: HY-B0035AR
CAS No.: 1981-58-4
Synonyms: Sulfadimidine sodium (Standard); Sulfadimerazine sodium (Standard)
Research Areas:  

Infection

Sulfamethazine sodium (Standard) is the analytical standard of Sulfamethazine sodium (HY-B0035A). This product is intended for research and analytical applications. Sulfamethazine (Sulfadimidine) sodium is a brain-penetrant sulfonamide antibiotic. Sulfamethazine sodium inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine sodium can be used for research on bacterial infections .
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Cat. No.: HY-W585867
CAS No.: 132898-07-8
Target:  

Drug Derivative

Research Areas:  

Others

4,7,8-TriMeIQx is a mutagenic imidazoquinoxaline and chemical in bacterial systems (Ames test) as well as active in the DNA repair test in liver cells.
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Cat. No.: HY-187377
Target:  

Glycosidase

α-Glucosidase-IN-121 is a yeast α-glucosidase inhibitor with an IC50 of 3.8 μM and a Ki of 12.9 μM. α-Glucosidase-IN-121 binds to the active site of the enzyme, competes with substrate binding, and forms stable interactions with Phe137, Ser308, Pro309, Arg312 and Glu350 via hydrogen bonding, π-π stacking and hydrophobic interactions. α-Glucosidase-IN-121 can be used in the research of diabetes .
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Cat. No.: HY-24366
CAS No.: 2423-66-7
Research Areas:  

Infection

Quindoxin is an antibacterial and growth promoter, commonly used in the livestock industry. Quindoxin exhibits clear dose-dependent mutagenic activity against Salmonella typhimurium TA98 and TA100 strains. Quindoxin can cause DNA damage and has potential genotoxicity and carcinogenic risks .
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Cat. No.: HY-W040279
CAS No.: 94125-34-5
Research Areas:  

Others

Prosulfuron is a fluorinated sulfonylurea herbicide with a reported acute oral LD50 of 546 mg/kg in female rats. Prosulfuron acts by inhibiting acetolactate synthase (ALS) to block the biosynthesis of branched-chain amino acids (valine, leucine and isoleucine) in plants, thereby suppressing weed growth. Prosulfuron may disrupt the soil microbial community balance in alkaline soils with minimal chemical degradation. Prosulfuron has low toxicity to humans and mammals, and can be used for the research of broadleaf weed control in maize and sweet corn .
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Cat. No.: HY-182366
EED-IN-5 is an orally active, EZH2-selective trisubstituted pyridine-based EED-H3K27me3 inhibitor and immunomodulator with anti-inflammatory activity. The IC50 value of EED-IN-5 against EED is 28.21 nM. In mouse models, EED-IN-5 preferentially and persistently accumulates in lymph nodes after oral administration. By reducing the H3K27me3 level of dendritic cells and inhibiting their migration, EED-IN-5 decreases the infiltration of specific dendritic cells, macrophages and T cells into the spinal cord and brain. EED-IN-5 exhibits hERG inhibitory activity, shows negative results in the Mini-Ames test, and causes no obvious toxicity upon long-term high-dose administration. EED-IN-5 can be used for the research of multiple sclerosis .
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