8 Results for "

Aquaporin-1

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Aquaporin-1" in MCE Product Catalog:

Cat. No.: HY-174166
CAS No.: 1021869-59-9
Target:  

Aquaporin

Research Areas:  

Metabolic Disease

AqF026 is an aquaporin 1 (AQP1) agonist. AqF026 enhances the channel activity of human AQP1 in the Xenopus laevis oocyte system. AqF026 enhances the osmotic transport of water across the peritoneum in a mouse model of peritoneal dialysis. AqF026 can be used in studies related to ultrafiltration failure in peritoneal dialysis [1] .
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Cat. No.: HY-N4246
CAS No.: 382148-47-2
Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases [1] .
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Cat. No.: HY-N6016R
CAS No.: 382146-66-9
Bacopaside II (Standard) is the analytical standard of Bacopaside II. This product is intended for research and analytical applications. Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis [1] .
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Cat. No.: HY-P72086
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AQP1; Aquaporin 1 (Channel-Forming Integral Protein, 28kDa); Prev. CO; Aquaporin 1, Colton Blood Group Antigen; CHIP28; Aquaporin 1 Splice Variant 2; Aquaporin-CHIP; Colton Blood Group Antigen; Aquaporin-1; Bloodgroup CO Protein; Aquaporin 1 (Channel-Form
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72085
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AQP1; Aquaporin 1 (Channel-Forming Integral Protein, 28kDa); Prev. CO; Aquaporin 1, Colton Blood Group Antigen; CHIP28; Aquaporin 1 Splice Variant 2; Aquaporin-CHIP; Colton Blood Group Antigen; Aquaporin-1; Bloodgroup CO Protein; Aquaporin 1 (Channel-Form
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P86699
Synonyms: AQP 1; AQP-1; AQP1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; AQP CHIP; AQP1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.

Host:  

Rabbit

Application:  

WB, IF-Tissue, IHC-P, IHC-F

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81404A
Synonyms: AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81404
Synonyms: AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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