1 Result for "

Azetukalner

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Azetukalner" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-139791
CAS No.: 1009344-33-5
Purity:  99.61%
Synonyms: XEN1101
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Azetukalner (XEN1101) is a selective and orally active Kv7.2/Kv7.3 potassium channel opener with an EC50 of 27 nM. Azetukalner is approximately 4-fold more selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50 of 94 nM) and Kv7.4 (EC50 of 113 nM) channels. Azetukalner exhibits a selectivity >100-fold for Kv7 channels over other ion channels and receptors. Azetukalner can be used for the study of focal epilepsy .
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