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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
BAZ2A
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "BAZ2A" in MCE Product Catalog:
3
3 Cited Publications
Target:
연구분야:
GSK2801, a chemical probe, is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4 .
2
2 Cited Publications
Cat. No.: HY-19336
CAS No.: 1665195-94-7
Target:
연구분야:
BAZ2-ICR is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. BAZ2-ICR is an epigenetic chemical probe .
Target:
연구분야:
GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments .
Cat. No.: HY-RS01379
Target:
연구분야:
BAZ2A Human Pre-designed siRNA Set A contains three designed siRNAs for BAZ2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18165
Target:
연구분야:
Baz2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Baz2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168449
BAZ2A/B ligand 1 (compound 1) is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). BAZ2A/B ligand 1 can be used for synthesis dBAZ2 (HY-168448) .
Cat. No.: HY-77826
CAS No.: 220000-87-3
Target:
연구분야:
4-Chloro-N-methylpicolinamide (Compound 3) is a BAZ2A bromodomain inhibitor with a Kd of >500 μM. 4-Chloro-N-methylpicolinamide forms a weak hydrogen bond with the carbonyl oxygen of Pro1817. 4-Chloro-N-methylpicolinamide can be used in the research of invasive prostate cancer .
Cat. No.: HY-RS24639
Target:
연구분야:
Baz2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Baz2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168448
CAS No.: 3104449-57-9
Target:
연구분야:
dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449)) .
Cat. No.: HY-168453
CAS No.: 3104449-58-0
Target:
연구분야:
dBAZ2B is a BAZ2B PROTAC degrader, with a DC50 of 19 nM . (Pink: BAZ2A/B ligand (HY-168449); Black: linker (HY-168450); Blue: VHL Ligand (HY-125905))
Cat. No.: HY-107477R
CAS No.: 1693766-04-9
연구분야:
GSK8573 (Standard) is the analytical standard of GSK8573 (HY-107477). This product is intended for research and analytical applications. GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
