2 Results for "

BMS358233

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BMS358233" in MCE Product Catalog:

Cat. No.: HY-121849
CAS No.: 819868-62-7
Target:  

Src

Research Areas:  

Cancer

BMS-358233 (compound 3) is a Lck inhibitor (IC50: 1 nM; Ki: 540 pM) and inhibits T cell proliferation (IC50: 262 nM).
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Cat. No.: HY-120625
CAS No.: 601519-75-9
Target:  

HSP

Research Areas:  

Cancer

PU3 is a small molecule inhibitor of Hsp90 that competes with geldanamycin for Hsp90. PU3 induces degradation of proteins, including Her2, similar to geldanamycin. PU3 inhibits the growth of breast cancer cells, causing retinoblastoma protein hypophosphorylation, G1 arrest, and differentiation. PU3 represents a novel class of synthetic compounds that bind to Hsp90 and inhibit the proliferation of cancer cells. PU3 could provide a new strategy for the treatment of cancers .
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