1 Result for "

BMS871

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BMS871" in MCE Product Catalog:

Cat. No.: HY-120372
CAS No.: 1584631-89-9
Target:  

Notch

Research Areas:  

Cancer

BMS-871 is an orally active pan-Notch inhibitor with IC50 values ​​of 4/1/4/3 nM for Notch1/2/3/4, respectively. BMS-871 significantly inhibited the proliferation of TALL-1 and MDA-MB-157 cells and demonstrated significant antitumor activity in T-acute lymphoblastic leukemia and triple-negative breast cancer xenograft models. BMS-871 can be used to study leukemia and breast cancer .
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