4 Results for "

BTK-IN-12

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "BTK-IN-12" in MCE Product Catalog:

Cat. No.: HY-147582
CAS No.: 2762043-53-6
Target:  

Btk

Research Areas:  

Cancer

BTK-IN-12 is a potent BTK inhibitor with IC50s of 1.2 nM and 0.8 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022037649A1; compound 8) .
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Cat. No.: HY-49421
CAS No.: 1791402-91-9
Research Areas:  

Cancer

BTK ligand 12 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). BTK ligand 12 can serve as an active control for the target protein ligand of NRX-0492 (HY-153357) .
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Cat. No.: HY-170413
CAS No.: 2736508-65-7
Target:  

PROTACs Btk

Research Areas:  

Cancer

PROTAC BTK Degrader-12 is a BTK PROTAC degrader that recruits CRBN, with a DC50 of 0.72 nM. PROTAC BTK Degrader-12 achieves ubiquitin-proteasome pathway degradation of BTK by conjugating a BTK inhibitor domain with an E3 ubiquitin ligase ligand domain. PROTAC BTK Degrader-12 can be used in cancer research .
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Cat. No.: HY-W245311
CAS No.: 2703915-71-1
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413) .
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