7 Results for "

Baccatin III

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Baccatin III" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N6985
CAS No.: 27548-93-2
Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition, and shows potential in the treatment of pulmonary fibrosis and cancer in terms of regulating the tumor immune microenvironment .
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Cat. No.: HY-N6985R
CAS No.: 27548-93-2
Baccatin III (Standard) is the analytical standard of Baccatin III. This product is intended for research and analytical applications. Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs .
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Cat. No.: HY-W777110
CAS No.: 115437-21-3
Synonyms: 7-O-(Triethylsilyl)Baccatin III
Target:  

Drug Intermediate

Research Areas:  

Cancer

7-(Triethylsilyl)baccatin III (7-O-(Triethylsilyl)baccatin III) is intermediate for preparation of the antitumor agent Paclitaxel (HY-B0015) .
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Cat. No.: HY-N8070
CAS No.: 220932-65-0
Synonyms: Baccatin III 13-cinnamate
Target:  

Drug Derivative

Research Areas:  

Others

13-O-Cinnamoylbaccatin III (Baccatin III 13-cinnamate) is a taxane that can be found in the twigs of Taxus mairei .
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Cat. No.: HY-W778546
CAS No.: 71629-92-0
7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
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Cat. No.: HY-W778547
CAS No.: 151636-94-1
Synonyms: 10-DehydroBaccatin V
7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
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Cat. No.: HY-W778558
CAS No.: 171926-87-7
Target:  

Drug Derivative

Research Areas:  

Others

2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III is a Baccatin III (HY-N6985) derivative lacking a benzoyl residue. 2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III can be isolated from the needles of the European yew (T. barcata L.) .
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