1 Result for "

Balcinrenone

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Balcinrenone" in MCE Product Catalog:

Cat. No.: HY-120274
CAS No.: 1850385-64-6
Purity:  99.96%
Synonyms: AZD9977
Balcinrenone (AZD9977) is an orally active mineralocorticoid receptor modulator. Balcinrenone regulates mineralocorticoid receptor activity, inhibits aldosterone-induced target gene expression, and suppresses the activities of renal Toll-like receptor 4, MyD88 and NF-κB. Balcinrenone alleviates renal extracellular matrix remodeling, inflammatory cell infiltration, and the expression of renal injury markers. Balcinrenone restores myocardial perfusion reserve, regulates potassium homeostasis, and induces fecal potassium excretion. Balcinrenone is applicable to research on metabolism-related chronic kidney disease and heart failure .
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