2 Results for "

C126

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "C126" in MCE Product Catalog:

Cat. No.: HY-161242A
Target:  

Bcl-2 Family

Research Areas:  

Cancer

CBI1 formic is a covalent BAX inhibitor. CBI1 formic selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 formic blocks t-2-hex lipidation and oligomerization of BAX. CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
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Cat. No.: HY-161242
Target:  

Bcl-2 Family

Research Areas:  

Cancer

CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
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