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Results for "

CACNB4

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149662
    TMDJ-035

    		Calcium Channel ATP Synthase Myosin Cardiovascular Disease
    TMDJ-035 is a high-affinity, selective RyR2 inhibitor with an EC50 of 0.0130 μM. TMDJ-035 reduces RyR2 protein expression without affecting action potential-induced Ca 2+ transients. TMDJ-035 decreases ATP content and intracellular Ca 2+ levels. TMDJ-035 inhibits arrhythmias in a CPVT mouse model carrying mutant RyR2s. TMDJ-035 has no effect on electrocardiogram parameters or cardiac systolic function. TMDJ-035 exacerbates heart failure in mouse myocardial infarction models and hypoxic cardiomyocytes by altering cardiac function, causing tissue damage, promoting inflammatory infiltration, collagen deposition, and changes in Myosin heavy chain/actin expression. TMDJ-035 can be used in studies related to heart failure, catecholaminergic polymorphic ventricular tachycardia, and arrhythmias .
    TMDJ-035
  • HY-RS01808
    CACNB4 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CACNB4 Human Pre-designed siRNA Set A contains three designed siRNAs for CACNB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CACNB4 Human Pre-designed siRNA Set A
    CACNB4 Human Pre-designed siRNA Set A

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