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CC-99282

" in MedChemExpress (MCE) Product Catalog:
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Cat. No.: HY-146237
CAS No.: 2379572-34-4
Purity:  98.04%
Synonyms: CC-99282
Research Areas:  

Cancer

Golcadomide (CC-99282) is a potent and orally active CRBN E3 ligase modulator (CELMoD). Golcadomide interacts with the CRL4 CRBN E3 ubiquitin ligase substrate receptor CRBN, inducing the recruitment and ubiquitin-mediated proteasomal degradation of the transcription factors Ikaros and Aiolos. Golcadomide shows potential for research in cancer-related fields, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL) .
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