1 Result for "

CFON-026

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CFON-026" in MCE Product Catalog:

Cat. No.: HY-174850
CAS No.: 2941611-57-8
Target:  

Btk

Research Areas:  

Cancer

CFON-026 is a selective, orally active and non-covalent BTK inhibitor with an IC50 of 0.27  nM. CFON-026 has significant antitumor activity against wild-type BTK (TMD8 and REC-1) and all clinically relevant BTK resistance mutations (BTK C481S, T474I, L528W and V416L). CFON-026 induces complete tumor regression in TMD8 xenograft mice model. CFON-026 can be used for research of hematological cancers like chronic lymphocytic leukemia and waldenström macroglobulinemia .
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