4 Results for "

CLM3

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CLM3" in MCE Product Catalog:

Cat. No.: HY-W012848
CAS No.: 618-36-0
Synonyms: DL-α-Methylbenzylamine
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease Cancer

1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413) .
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Cat. No.: HY-164413
CAS No.: 1312024-59-1
Target:  

VEGFR EGFR RET Apoptosis

Research Areas:  

Cancer

CLM3, a pyrazolopyrimidine derivative, is a multiple tyrosine kinase inhibitor. CLM3 shows antiproliferative and proapoptotic activity on endothelial and cancer cells, synergistically enhanced by SN38 (HY-13704). These effects are mainly due to its inhibition of phosphorylation of VEGFR-2, EGFR and RET tyrosine kinases and their related signaling pathways .
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Cat. No.: HY-RS21544
Research Areas:  

Others

Cyth3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cyth3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-W115741S
CAS No.: 474267-40-8
Synonyms: (±)-1-Phenylethylamine-d3; DL-alpha-Methylbenzylamine-d3
1-Phenylethanamine-d3 ((±)-1-Phenylethylamine-d3) is the deuterium labeled 1-Phenylethanamine (HY-W012848). 1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413).
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