1 Result for "

CM310

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CM310" in MCE Product Catalog:

Cat. No.: HY-P990093
CAS No.: 2734715-10-5
Synonyms: CM310

Research Areas:  

Inflammation/Immunology

Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα (KD values of 0.25 nM, 1.50 nM, and 2.75 nM for human, cynomolgus monkey, and rat IL-4Rα, respectively). Stapokibart effectively blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4Rα. Stapokibart reduces IL-4 and IL-13 mRNA, inhibits CD23 upregulation, and inhibits IL-4 and IL-13-induced STAT6 activation. Stapokibart improves inflammation (airway inflammation, rhinitis, dermatitis) .
loading...
    loading...