1 Result for "

CMLD012612

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CMLD012612" in MCE Product Catalog:

Cat. No.: HY-129767
CAS No.: 2368900-35-8
Research Areas:  

Cancer

CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity .
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