1 Result for "

CRCD2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CRCD2" in MCE Product Catalog:

Cat. No.: HY-167710
CAS No.: 941185-83-7
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

CRCD2 is a small molecule NT5C2 nucleotidase inhibitor with enhanced 6-mercaptopurine cytotoxic activity. CRCD2 can effectively reverse 6-mercaptopurine resistance caused by mutations in the NT5C2 gene or non-genetic activation mechanisms. CRCD2 combined with 6-mercaptopurine can enhance its cytotoxic activity in NT5C2 wild-type leukemia, showing its potential in the treatment of acute lymphoblastic leukemia .
loading...
    loading...