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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
CW 10201
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "CW 10201" in MCE Product Catalog:
Cat. No.: HY-189305
CW-10201 is a KRAS G12D and KRAS G12V PROTAC degrader with DC50 values of 4.0 nM. CW-10201 induces ubiquitination and degradation of KRAS G12D and KRAS G12V. CW-10201 mildly inhibits pERK1/2. CW-10201 does not induce degradation of IKZF1 and GSPT1. CW-10201 exhibits anticancer activity against pancreatic cancer and colorectal cancer. CW-10201 can be used for research on pancreatic cancer and colorectal cancer .
Cat. No.: HY-189349
Research Areas:
KRAS ligand-7 is a ligand for KRAS and can be used in research related to PROTAC synthesis. KRAS ligand-7 can serve as the target protein ligand for CW-10201 (HY-189305) .
Cat. No.: HY-189348
CAS No.: 3064305-88-7
Target:
Research Areas:
AA-17010 is a Cereblon ligand with an IC50 of 0.20 μM and a Ki of 0.08 μM. AA-17010 serves as an E3 ligase ligand for the synthesis of PROTAC KRAS degraders, such as CW-10201 (HY-189305) .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
