1 Result for "

CW8001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CW8001" in MCE Product Catalog:

Cat. No.: HY-174132
Target:  

CRM1

Research Areas:  

Inflammation/Immunology

CW8001 is a covalent XPO1 (Exportin-1) inhibitor with an EC50 value of 1 nM for inhibiting T cell activation. CW8001 prevents nuclear localization of NFAT transcription factors, suppressing expression of inflammatory cytokines like IL-2. CW8001 is promising for research of T cell-driven immune diseases such as graft-versus-host disease (GVHD) .
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