1 Result for "

Cbl-b-IN-30

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cbl-b-IN-30" in MCE Product Catalog:

Cat. No.: HY-179617
Research Areas:  

Cancer

Cbl-b-IN-30 is an orally active Casitas B-lineage lymphoma-b (CBLB) inhibitor. Cbl-b-IN-30 specifically binds to CBLB and inhibits its E3 ubiquitin ligase activity with an IC50 of 9.1 nM. Cbl-b-IN-30 can promote IL-2 secretion (EC50 = 187.5 nM) and enhance T cell activation. Cbl-b-IN-30 exerts antitumor activity and can induce immune memory. Cbl-b-IN-30 can be used for the research of colon cancer .
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