8 Results for "

Clofibrate

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Clofibrate" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-B0287
CAS No.: 637-07-0
Target:  

PPAR

Research Areas:  

Metabolic Disease

Clofibrate is an agonist of PPAR, with EC50s of 50 μM, ~500 μM for murine PPARα and PPARγ, and 55 μM, ~500 μM for human PPARα and PPARγ, respectively.
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Cat. No.: HY-107348
CAS No.: 54504-70-0
Purity:  99.77%
Research Areas:  

Cardiovascular Disease

Etofylline clofibrate has ypolipidemic and antithrombotic effect. Etofylline clofibrate has an agonistic interaction with intimal PGI2 .
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Cat. No.: HY-B0287R
CAS No.: 637-07-0
Research Areas:  

Metabolic Disease

Clofibrate (Standard) is the analytical standard of Clofibrate. This product is intended for research and analytical applications. Clofibrate is an agonist of PPAR, with EC50s of 50 μM, ~500 μM for murine PPARα and PPARγ, and 55 μM, ~500 μM for human PPARα and PPARγ, respectively.
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Cat. No.: HY-156977
CAS No.: 55902-94-8
Target:  

PPAR

Research Areas:  

Cardiovascular Disease

Sitofibrate is a Clofibrate (HY-B0287) derivative. Sitofibrate is aperoxisome proliferator activated receptor-α (PPAR-α) agonist. Sitofibrate is an antihyperlipidemic agent .
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Cat. No.: HY-107348R
CAS No.: 54504-70-0
Research Areas:  

Cardiovascular Disease

Etofylline clofibrate (Standard) is the analytical standard of Etofylline clofibrate. This product is intended for research and analytical applications. Etofylline clofibrate has ypolipidemic and antithrombotic effect. Etofylline clofibrate has an agonistic interaction with intimal PGI2 .
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Cat. No.: HY-B0287S
CAS No.: 1189654-03-2
Clofibrate-d4 is the deuterium labeled Clofibrate. Clofibrate is an agonist of PPAR, with EC50s of 50 μM, ∼500 μM for murine PPARα and PPARγ, and 55 μM, ∼500 μM for human PPARα and PPARγ, respectively.
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Cat. No.: HY-B1520
CAS No.: 24818-79-9
Synonyms: Aluminum Clofibrate
Target:  

PPAR

Research Areas:  

Cancer

Aluminium clofibrate is an orally active peroxisome proliferator. Aluminium clofibrate increases peroxisomal β-oxidation enzyme activities, elevates catalase. Aluminium clofibrate can be used in the research of cancer .
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Cat. No.: HY-14998
CAS No.: 26718-25-2
Synonyms: MK 185
Target:  

β-catenin PPAR Wnt

Research Areas:  

Endocrinology

Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .
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