1 Result for "

Crizotinib-d5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Crizotinib-d5" in MCE Product Catalog:

Cat. No.: HY-50878S
CAS No.: 1395950-84-1
Synonyms: PF-02341066-d5
Crizotinib-d5 is the deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition .
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