4 Results for "

DAMPA

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "DAMPA" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-108251
CAS No.: 19741-14-1
Purity:  98.44%
Synonyms: DAMPA
Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .
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Cat. No.: HY-108251R
CAS No.: 19741-14-1
Synonyms: DAMPA (Standard)
Methotrexate metabolite (Standard) is the analytical standard of Methotrexate metabolite. This product is intended for research and analytical applications. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent .
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Cat. No.: HY-108251S
CAS No.: 1794780-00-9
Synonyms: DAMPA-d3
Methotrexate metabolite-d3 is the deuterium labeled Methotrexate metabolite. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent .
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Cat. No.: HY-134133
CAS No.: 23853-09-0
Research Areas:  

Cancer

DAMPA methyl ester is an inhibitor of dihydrofolate reductase. DAMPA methyl ester can be studied in research on chemotherapy .
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