1 Result for "

DB1055

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DB1055" in MCE Product Catalog:

Cat. No.: HY-124693
CAS No.: 869767-86-2
Target:  

Apoptosis

Research Areas:  

Cancer

DB1055 is a HOXA9 inhibitor that competes with HOXA9 binding to DNA (blocking its DNA interaction activity). DB1055 induces in vitro cell growth reduction, cell apoptosis, and differentiation in human acute myeloid leukemia (AML) cells. DB1055 leads to monocyte-to-macrophage differentiation and exhibits antileukemic activities in a human THP-1 AML in vivo model. DB1055 does not impact human CD34+ bone marrow cells. DB1055 can be used for the research of acute myeloid leukemia[1].
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