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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Diamine oxidase
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Diamine oxidase" in MCE Product Catalog:
Target:
Research Areas:
Diamine oxidase (DAO) is an orally active enzyme. Diamine oxidase catalyzes oxidative deamination of various polyamines. Diamine oxidase degrades histamine and polyamines to maintain the metabolic balance of amines in the body. Diamine oxidase is a key regulatory enzyme in rapidly proliferating tissues such as bone marrow and intestinal mucosa. Diamine oxidase can be used in research related to intestinal diseases, small bowel transplant rejection, histamine intolerance, and other conditions .
10
10 Publications Verification
Synonyms: Pimagedine hydrochloride; GER-11; Aminoguanidinium hydrochloride
Target:
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .
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10 Publications Verification
Cat. No.: HY-W020772
CAS No.: 996-19-0
Synonyms: Pimagedine hemisulfate; GER-11 hemisulfate; Aminoguanidinium hemisulfate
Target:
Aminoguanidine (Pimagedine) hemisulfate is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hemisulfate can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hemisulfate has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hemisulfate has antioxidant properties. Aminoguanidine hemisulfate can be used in the research of diabetic nephropathy .
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1 Cited Publications
Cat. No.: HY-P7497
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AOC1; Amiloride-Binding Protein 1; Prev. ABP1; Histaminase; Prev. ABP; KDAO; DAO; KAO; Diamine oxidase; Amiloride-Sensitive Amine oxidase; Amiloride Binding Protein 1 (Amine oxidase (Copper-Containing)); Amiloride-Binding Protein; Amine oxidase Copper Dom
Species:
Human
Source:
HEK293
Synonyms: Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
Target:
Research Areas:
3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .
Target:
Aminoguanidine (Pimagedine) is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine has antioxidant properties. Aminoguanidine can be used in the research of diabetic nephropathy .
Cat. No.: HY-161794A
Target:
Research Areas:
SP3N hydrochloride is a specific degrader of the prolyl isomerase FKBP12. As a prodrug, SP3N hydrochloride is metabolized by Diamine oxidase into the active aldehyde metabolite SP3CHO (HY-161795). SP3N hydrochloride induces the proximity of FKBP12 to the SCF FBXO22 E3 ligase complex, thereby triggering the polyubiquitination and proteasomal degradation of FKBP12. SP3N hydrochloride can be used in cancer research .
Cat. No.: HY-P2888A
CAS No.: 80619-01-8
Synonyms: BOD, bacillus cereus
Target:
Research Areas:
Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors .
Cat. No.: HY-P2888C
Synonyms: BOD, Bacillus pumilus
Target:
Research Areas:
Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors .
Cat. No.: HY-161794
Target:
Research Areas:
SP3N is a specific degrader of the prolyl isomerase FKBP12. As a prodrug, SP3N is metabolized by Diamine oxidase into the active aldehyde metabolite SP3CHO (HY-161795). SP3N induces the proximity of FKBP12 to the SCF FBXO22 E3 ligase complex, thereby triggering the polyubiquitination and proteasomal degradation of FKBP12. SP3N can be used in cancer research .
Cat. No.: HY-B1041AS
CAS No.: 478189-68-3
Synonyms: Pimagedine-13C, 15N4; GER-11free base-13C, 15N4; Aminoguanidinium-13C, 15N4
Aminoguanidine- 13C, 15N4 (Pimagedine- 13C, 15N4) is the 13C, 15N4-labeled Aminoguanidine (HY-W020772). Aminoguanidine is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine has antioxidant properties. Aminoguanidine can be used in the research of diabetic nephropathy .
Synonyms: Pimagedine hydrochloride (Standard); GER-11 (Standard); Aminoguanidinium chloride (Standard)
Target:
Research Areas:
Aminoguanidine (hydrochloride) (Standard) is the analytical standard of Aminoguanidine (hydrochloride). This product is intended for research and analytical applications. Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research .
Cat. No.: HY-W020772AS1
Synonyms: Pimagedine-13C,15N4 hemisulfate; GER-11-13C,15N4 hemisulfate; Aminoguanidinium-13C,15N4 hemisulfate
Cat. No.: HY-187102
CAS No.: 19866-38-7
Target:
Research Areas:
2-Hydrazinyl-3-methylbutanoic acid is a diamine oxidase (DAO) inhibitor. 2-Hydrazinyl-3-methylbutanoic acid acts as a non-competitive inhibitor of diamine oxidase (with histamine as the substrate), achieving an inhibition rate of up to 76%. This inhibition can be prevented by pre-incubation with 2-Ketoglutaric acid (HY-W013636) to form a non-inhibitory complex. 2-Hydrazinyl-3-methylbutanoic acid also inhibits glutamate decarboxylase and 5-hydroxytryptophan decarboxylase, and exhibits moderate inhibitory activity against monoamine oxidase. 2-Hydrazinyl-3-methylbutanoic acid can be used in studies related to amino acid metabolic enzymes .
Cat. No.: HY-Y0047S
Synonyms: Picolamine-d2; 3-Pyridinemethanamine-d2; Pyridin-3-ylmethanamine-d2
Cat. No.: HY-W020772AS
Synonyms: Pimagedine-13C,15N2 hemisulfate; GER-11-13C,15N2 hemisulfate; Aminoguanidinium-13C,15N2 hemisulfate
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
