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Diamine oxidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Biochemical Assay Reagents (5) Endogenous Metabolite (2) ERK (1) Fungal (2) Isotope-Labeled Compounds (1) NO Synthase (4) Reference Standards (1)
By Research Areas:	Cancer (1) Endocrinology (3) Inflammation/Immunology (3) Metabolic Disease (9) Neurological Disease (1)

Inhibitors & Agonists

Antibodies

Targets Recommended: Amino Acid Oxidase Lysyl Oxidase Glycolate Oxidase Aldehyde Oxidase (AO) Xanthine Oxidase NADPH Oxidase Monoamine Oxidase Protoporphyrinogen IX oxidase VAP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1041

Aminoguanidine hydrochloride 5+ Cited Publications Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride	NO Synthase Apoptosis ERK	Neurological Disease Metabolic Disease Inflammation/Immunology
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .

HY-P2758

**Diamine oxidase** DAO	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology Cancer
Diamine oxidase (DAO) is an orally active enzyme. Diamine oxidase catalyzes oxidative deamination of various polyamines. Diamine oxidase degrades histamine and polyamines to maintain the metabolic balance of amines in the body. Diamine oxidase is a key regulatory enzyme in rapidly proliferating tissues such as bone marrow and intestinal mucosa. Diamine oxidase can be used in research related to intestinal diseases, small bowel transplant rejection, histamine intolerance, and other conditions .

HY-Y0047

3-Picolylamine Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine	Biochemical Assay Reagents	Inflammation/Immunology
3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .

HY-B1041A

Aminoguanidine Pimagedine; GER-11free base ; Aminoguanidinium	NO Synthase Apoptosis	Endocrinology
Aminoguanidine (Pimagedine hydrochloride) is an inhibitor of **diamine oxidase and nitric oxide synthase. Aminoguanidine has a dose-dependent inhibitory effect on apoptosis** induced by Doxorubicin (HY-15142). Aminoguanidine has antioxidant properties. Aminoguanidine can be used in diabetic nephropathy research .

HY-P2888A

Bilirubin oxidase, bacillus cereus BOD, bacillus cereus	Endogenous Metabolite	Metabolic Disease
Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors .

HY-P2888C

Bilirubin oxidase, Bacillus pumilus BOD, Bacillus pumilus	Endogenous Metabolite	Metabolic Disease
Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors .

HY-B1041AS

Aminoguanidine-13C, 15N4 Pimagedine-13C, 15N4; GER-11free base-13C, 15N4; Aminoguanidinium-13C, 15N4	Isotope-Labeled Compounds NO Synthase Apoptosis	Endocrinology
Aminoguanidine- ¹³C, ¹⁵N₄ (Pimagedine- ¹³C, ¹⁵N₄) is the ¹³C- and ¹⁵N-labeled Aminoguanidine (HY-B1041A). Aminoguanidine (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine has antioxidant properties. Aminoguanidine can be used in diabetic nephropathy research .

HY-B1041R

Aminoguanidine hydrochloride (Standard) Pimagedine hydrochloride (Standard); GER-11 (Standard); Aminoguanidinium chloride (Standard)	NO Synthase Apoptosis Reference Standards	Endocrinology
Aminoguanidine (hydrochloride) (Standard) is the analytical standard of Aminoguanidine (hydrochloride). This product is intended for research and analytical applications. Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research .

HY-P2890D

Laccase, Agaricus bisporus	Biochemical Assay Reagents	Metabolic Disease
Laccase, Agaricus bisporus (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.

HY-P2890H

Laccase, Pleurotus ostreatus (mushroom)	Biochemical Assay Reagents	Metabolic Disease
Laccase, Pleurotus ostreatus (mushroom) (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.

HY-P2890I

Laccase, White rot fungi	Biochemical Assay Reagents	Metabolic Disease
Laccase, White rot fungi (EC 1.10.3.2) is a blue copper oxidase that reduces molecular oxygen to water. Laccase oxidizes polyphenols, methoxy-substituted phenols and diamines, but not tyrosine. Oxidation by laccase is an one-electron reaction that generates a free radical.

HY-P2890B

Laccase, Trametes versicolor	Fungal	Metabolic Disease
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.

HY-P2890C

Laccase, Rhus vernicifera	Fungal	Metabolic Disease
Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89625

	ABP1 Antibody (YA8969) Abp1, Aoc1, Diamine oxidase [copper-containing], Diamine oxidase, Amine oxidase copper domain-containing protein 1, Histaminase	WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA	human
	ABP1 Antibody (YA8969) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ABP1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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