1 Result for "

EG31

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EG31" in MCE Product Catalog:

Cat. No.: HY-172966
CAS No.: 360760-58-3
Target:  

EGFR

Research Areas:  

Cancer

EG31 is an EGFR inhibitor. EG31 effectively inhibits the proliferation of triple-negative breast cancer (TNBC) cells (GI50 values of MDA-MB-231 and Hs578T cells are 498.90 nM and 740.73 nM, respectively) and induces apoptosis by inhibiting the EGFR signaling pathway. EG31 still maintains antiproliferative activity against 5-fluorouracil (5-FU)-resistant TNBC cells (GI50: 519.5 nM). EG31 can be used to study TNBC resistance .
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