1 Result for "

EMA402

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EMA402" in MCE Product Catalog:

Cat. No.: HY-19202
CAS No.: 152362-51-1
Synonyms: rac-EMA401; rac-PD-126055; EMA400
Target:  

Angiotensin Receptor

Research Areas:  

Neurological Disease

rac-Olodanrigan (rac-EMA401; EMA400) is a racemic mixture of the S-enantiomer (EMA401; HY-13106) and R-enantiomer (EMA402). rac-Olodanrigan is a potent and selective AT2 receptor antagonist with IC50s of 75.2 nM and 2918 nM for AT2R and AT1R, respectively. rac-Olodanrigan evokes dose-dependent relief of mechanical allodynia in the ipsilateral hind paws of rats with a chronic constriction injury (CCI) of the sciatic nerve .
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