45 Results for "

EU

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "EU" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-113920A
CAS No.: 64748-79-4
Purity:  99.11%
Synonyms: EU4093 free base
Target:  

Calcium Channel

Research Areas:  

Metabolic Disease

Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research .
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2
2 Cited Publications
Cat. No.: HY-141140
CAS No.: 69075-42-9
Purity:  98.19%
Synonyms: 5-EU
Research Areas:  

Others

5-Ethynyluridine (5-EU) is a potent cell-permeable nucleoside can be used to label newly synthesized RNA. 5-Ethynyluridine can be used for isolation and sequencing of nascent RNA from neuronal populations in vivo. 5-Ethynyluridine can be used to identify changes in transcription in vivo in nervous system disease models . 5-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1
1 Cited Publications
Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) (Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
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1
1 Cited Publications
Cat. No.: HY-P73143
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; Immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; Immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70796
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; Immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; Immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-125929
CAS No.: 3051-09-0
Purity:  ≥98.0%
Synonyms: Ammonium purpurate
Murexide is a coordinating dye and Eu 2+ ion-binding tool with utility for measuring dissociation rates of Eu 2+-containing cryptates and study of other Eu 2+ complexes .
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Cat. No.: HY-B1137
CAS No.: 3615-24-5
Synonyms: Isopropylaminoantipyrine
Target:  

COX Bacterial

Research Areas:  

Infection Inflammation/Immunology

Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation .
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Cat. No.: HY-101778
CAS No.: 315698-17-0
Purity:  98.98%
Synonyms: EU-5346
Target:  

Bcl-2 Family

Research Areas:  

Cancer

ML311 is a potent and selective inhibitor of the Mcl-1/Bim interaction.
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Cat. No.: HY-P991217

Research Areas:  

Cancer

EU-103 is a humanized monoclonal antibody targeting V-Set And Immunoglobulin Domain Containing 4 (VSIG4) with a KD value ranging from 10 −7 and 10 −9. EU-103 blocks the interaction between VSIG4 and CD8+ T cells, promotes the conversion of M2 macrophages into M1 macrophages, induces the proliferation of CD8+ T cells and the secretion of pro-inflammatory cytokines, thereby inhibiting tumor growth. EU-103 is promising for research of cancers, such as bladder cancer, breast cancer, and colon cancer .
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Cat. No.: HY-173623
CAS No.: 3057728-22-7
Target:  

iGluR

Research Areas:  

Neurological Disease

EU 1622-240 is a biased positive allosteric modulator of GluN2B, GluN2C, and GluN2D, with EC50s of 0.57, 0.82, 1.1 μM respectively. EU 1622-240 has good physicochemical properties, in vitro stability, and permeability .
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Cat. No.: HY-113920
CAS No.: 105336-14-9
Synonyms: EU4093
Target:  

Calcium Channel

Research Areas:  

Others

Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca 2+ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca 2+]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection .
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Cat. No.: HY-P991405

Target:  

TNF Receptor

Research Areas:  

Cancer

EU-102 is a human monoclonal antibody (mAb) targeting TNFSF18. EU-102 can be used in solid tumors research .
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Cat. No.: HY-P1204
CAS No.: 359784-84-2
Target:  

MCHR1 (GPR24)

Research Areas:  

Metabolic Disease

[Ala17]-MCH, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu 3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2 .
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Cat. No.: HY-153200
CAS No.: 2761969-85-9
Target:  

MDM-2/p53

Research Areas:  

Cancer

MDM2/XIAP-IN-2 is a dual inhibitor of murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP). MDM2/XIAP-IN-2 degrades MDM2, and inhibits XIAP mRNA translation to inhibits cancer cells. Particularly, MDM2/XIAP-IN-2 inhibits acute lymphoblastic leukemia cell line EU-1 with an IC50 value of 0.3 μM .
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Cat. No.: HY-P1204A
Target:  

MCHR1 (GPR24)

Research Areas:  

Metabolic Disease

[Ala17]-MCH TFA, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu 3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2 .
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Cat. No.: HY-B1137S
CAS No.: 1330180-51-2
Synonyms: Isopropylaminoantipyrine-d7
Ramifenazone-d7 (Isopropylaminoantipyrine-d7) is the deuterated-labeled Ramifenazone (HY-B1137). Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation .
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Cat. No.: HY-101778R
CAS No.: 315698-17-0
Synonyms: EU-5346 (Standard)
Research Areas:  

Cancer

ML311 (Standard) (EU-5346 (Standard)) is the analytical standard of ML311 (HY-101778). This product is intended for research and analytical applications. ML311 is a potent and selective inhibitor of the Mcl-1/Bim interaction.
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Cat. No.: HY-156505A
CAS No.: 2488764-06-1
Target:  

iGluR

Research Areas:  

Neurological Disease

R-(+)-EU-1180-453 is a positive allosteric modulator targeting NMDA receptors containing GluN2C and GluN2D subunits, with a pEC50 value of 5.5 for both rat receptor subtypes, and it can cross the blood-brain barrier. R-(+)-EU-1180-453 increases the potency of glutamate, enhances receptor responses to maximally effective concentrations of agonists, and acts only on receptors bound to both co-agonists. R-(+)-EU-1180-453 is applicable to research related to Alzheimer's disease, Parkinson's disease, epilepsy, and neuropathic pain .
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Cat. No.: HY-P992044
Synonyms: NOV1801
EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities .
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Cat. No.: HY-B1137R
CAS No.: 3615-24-5
Synonyms: Isopropylaminoantipyrine (Standard)
Ramifenazone (Isopropylaminoantipyrine) Standard is the analytical standard of Ramifenazone (HY-B1137). This product is intended for research and analytical applications. Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation .
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