2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. EU101

EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities.

For research use only. We do not sell to patients.

EU101

EU101 Chemical Structure

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EU101 Related Antibodies

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Description

EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities[1].

Species Reactivity

Human
In Vitro

EU101 can target and bind to CD137 expressed on various leukocyte subsets, enhance CD137-mediated signaling, induce the proliferation of cytotoxic T lymphocytes and cytokine production, and promote cytotoxic T lymphocyte-mediated anti-tumor immune responses. Meanwhile, it can also induce natural killer cell-mediated tumor cell killing and suppress the immunosuppressive activity of regulatory T cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EU101 Related Antibodies
Clinical Trial
Gene ID

3604  [NCBI]

Accession
Target

TNFRSF9/4-1BB/CD137
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
SMILES

[EU101]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EU101 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EU101NOV1801EU 101EU-101NOV 1801NOV-1801Transmembrane GlycoproteinhumanizedantibodyCD137Inhibitorinhibitorinhibit

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EU101
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HY-P992044
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