1 Result for "

Everafenib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Everafenib" in MCE Product Catalog:

Cat. No.: HY-150639
CAS No.: 2923700-82-5
Target:  

Raf

Research Areas:  

Cancer

Everafenib is a potent and blood-brain barrier (BBB) penetrant BRAF inhibitor, also inhibits MAPK signaling. Everafenib has inhibitory activity against a panel of V600EBRAF melanoma cell lines with IC50 values of 2-10 nM, which is better than Dabrafenib (HY-14660) and Vemurafenib (HY-12057). Everafenib has efficacy in an intracranial mouse model of metastatic melanoma .
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