1 Result for "

FD223

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FD223" in MCE Product Catalog:

Cat. No.: HY-132231
CAS No.: 2050524-24-6
Purity:  98.05%
Target:  

PI3K Apoptosis

Research Areas:  

Cancer

FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML .
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