6 Results for "

FH1

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "FH1" in MCE Product Catalog:

Cat. No.: HY-12346
CAS No.: 2719-05-3
Purity:  99.17%
Synonyms: NSC 12407; BRD-K4477
Target:  

Quinone Reductase

Research Areas:  

Others

FH1 (NSC 12407) is a NQO2 inhibitor with hepatoprotective effects. FH1 enhances hepatocyte function and promotes differentiation of induced pluripotent stem (iPS)-derived hepatocytes to a more mature phenotype and maturation of well-differentiated hepatocyte-like cell (iHeps) cultures. FH1 protects against Acetaminophen (HY-66005)-induced hepatotoxicity in both embryos and adult zebrafish [1] .
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Cat. No.: HY-P991067
CAS No.: 2724922-85-2
Synonyms: KP-104

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) [1]. [1].
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Cat. No.: HY-160875
CAS No.: 920115-54-4
Research Areas:  

Metabolic Disease

GST-FH.1 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC50 of 0.32 μM [1].
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Research Areas:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) comprising a humanized anti-C3d monoclonal antibody linked to two moieties of the first five consensus repeats of factor H (fH1-5). Ebribafusp alfa binds C3d and related fragments, catalyzes AP convertase dissociation, acts as a factor I co-factor for C3b cleavage, and delivers fH1-5 moieties to C3d-deposited tissues for local complement inhibition without systemic blockade. Ebribafusp alfa reduces glomerular C3 deposition, proteinuria, urine albumin-creatinine ratios, and urine soluble C5b-9 levels, preserves podocyte foot-process architecture, inhibits skin complement activation, and localizes to UVB-damaged primate skin. Ebribafusp alfa can be used for the research of membranous nephropathy, bullous pemphigoid, discoid lupus erythematosus, C3 glomerulopathy, IgA nephropathy, and lupus nephritis [1] .
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Cat. No.: HY-RS04980
Research Areas:  

Others

FLNB Human Pre-designed siRNA Set A contains three designed siRNAs for FLNB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23562
Research Areas:  

Others

Fh Rat Pre-designed siRNA Set A contains three designed siRNAs for Fh gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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