1 Result for "

G970R

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "G970R" in MCE Product Catalog:

Cat. No.: HY-103369
CAS No.: 853138-65-5
Purity:  ≥98.0%
Target:  

CFTR

Research Areas:  

Endocrinology

PG01 is a potent CFTR Cl - channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 (Ka of 0.3 μM). PG01 increases ΔF508-CFTR Cl - current after adding Forskolin .
loading...
    loading...