1 Result for "

GC1008

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GC1008" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99020
CAS No.: 948564-73-6
Synonyms: GC1008

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology Cancer

Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab improves Bleomycin (HY-108345)-induced acute lung injury. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease .
loading...
    loading...