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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
GNE616
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "GNE616" in MCE Product Catalog:
Cat. No.: HY-126291
CAS No.: 2349371-81-7
Target:
Research Areas:
GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain. GNE-616 shows >1000 nM Kd and >2500-fold selectivity over hNav1.1, hNav1.3, hNav1.4, and hNav1.5. Selectivity over hNav1.2 and hNav1.6 is more modest at 31- and 73-fold, respectively .
Cat. No.: HY-127107
CAS No.: 2244895-99-4
Target:
Research Areas:
(2S,4R)-GNE-616 (Example1) is a specific stereoisomer of GNE-616 (HY-126291). (2S,4R)-GNE-616 is a voltage-gated sodium channel (NaV1.7) inhibitor that can be used in research on sodium channel-mediated diseases such as pain .
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Protocols
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