1 Result for "

GSI-526

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GSI-526" in MCE Product Catalog:

Cat. No.: HY-183799
Target:  

PROTACs IRAK NF-κB p38 MAPK

Research Areas:  

Inflammation/Immunology

GSI526 is a IRAK4 PROTAC degrader (DC50=40.17 nM, Dmax=97%; THP-1) based on the VHL ubiquitin-proteasome system. GSI526 inhibits IRAK4-mediated NF-κB and MAPK inflammatory signaling pathways, and induces IRAK4 degradation in myeloid cells. GSI526 is applicable to inflammation-related research .
loading...
    loading...