1 Result for "

GeA-69

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "GeA-69" in MCE Product Catalog:

Cat. No.: HY-108708
CAS No.: 2143475-98-1
Pureté:  99.91%
Target:  

PARP

Domaines de recherche:  

Cancer

GeA-69 is a selective, allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2 (MD2), with a Kd value of 2.1 μM. GeA-69 involves in DNA damage repair mechanisms and prevents recruitment of PARP14 MD2 to sites of laser-induced DNA damage .
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