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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Glyoxalase I
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Glyoxalase I" in MCE Product Catalog:
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Glyoxalase I (Glo-I) is a glycosidase and a methylglyoxal (MOG) detoxification enzyme. Glyoxalase I can be used for the research of inflammation and cancer .
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5 Cited Publications
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Glyoxalase I inhibitor free base (3(Et)2) is the inhibitor for glyoxalase I (GLO), and can be used in antitumor research .
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1 Cited Publications
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Glyoxalase I inhibitor 6 (Compound 9j) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 1.13 μM. Glyoxalase I inhibitor 6 can be used as anticancer agent with low toxicity .
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Glyoxalase I inhibitor 5 (Compound 9h) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 1.28 μM. Glyoxalase I inhibitor 5 can be used as anticancer agent .
Cat. No.: HY-15167
CAS No.: 221174-33-0
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Glyoxalase I inhibitor (3(Et)2) is the inhibitor for glyoxalase I (GLO), and can be used in antitumor research .
Cat. No.: HY-126752A
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Ophthalmic acid TFA is a ubiquitous metabolite and glutathione modulator, with a Ki of 0.95 mM for glyoxalase I. Ophthalmic acid TFA competitively inhibits glyoxalase I, glutathione S-transferase, glutaredoxin, glutamate-cysteine ligase, protein disulfide reductase (glutathione), as well as non-selective cation channels. Ophthalmic acid TFA is applicable in diabetes-related research .
Cat. No.: HY-146653
CAS No.: 1622952-07-1
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Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 26 nM . Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-147649
CAS No.: 2455508-31-1
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Glyoxalase I inhibitor 7 (Compound 6) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 3.65 μM. Glyoxalase I inhibitor 7 can be used as anticancer agent .
Cat. No.: HY-146656
CAS No.: 250155-72-7
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Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an Ki of 10 nM .
Cat. No.: HY-146654
CAS No.: 2314467-61-1
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Glyoxalase I inhibitor 2 (compound 26) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.5 µM. Glyoxalase I inhibitor 2 has the potential for the research of depression and anxiety .
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Glyoxalase I inhibitor 3 (compound 22g) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.011 µM. Glyoxalase I inhibitor 3 has the potential for the research of depression and anxiety .
Cat. No.: HY-146657
CAS No.: 828262-76-6
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4BAB (compound 29) is an irreversible glyoxalase I (GLO1) inhibitor. 4BAB has anticancer effects .
Cat. No.: HY-126752R
CAS No.: 495-27-2
Cat. No.: HY-W842446
CAS No.: 58265-74-0
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Cat. No.: HY-P75162
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLO1; Aldoketomutase; Glyoxalase I; Glx I; Lactoylglutathione Lyase; Epididymis Secretory Protein Li 74; GLOD1; Glyoxalase Domain Containing 1; S-D-Lactoylglutathione Methylglyoxal Lyase; Lactoyl Glutathione Lyase; Ketone-Aldehyde Mutase; HEL-S-74; Methyl
Species:
Mouse
Source:
E. coli
Cat. No.: HY-117208
CAS No.: 748786-57-4
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TLSC702 is a human glyoxalase I (hGLO I) inhibitor with an IC50 of 2.0 μM. TLSC702 inhibits the activity of human glyoxalase I, thereby leading to the accumulation of methylglyoxal and its derived advanced glycation end products. TLSC702 inhibits tumor cell proliferation, induces apoptotic morphological changes, internucleosomal DNA fragmentation and PARP cleavage in tumor cells. TLSC702 can be used in research related to leukemia and lung cancer .
Cat. No.: HY-181980
CAS No.: 883054-47-5
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SPB07393SC is a glyoxalase-I (Glo-I) inhibitor with an IC50 of 11.1 μM. SPB07393SC is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
