495-27-2
495-27-2
Chemical Structure
Ophthalmic acid
- CAS. Nr.: 495-27-2
- Formula:C11H19N3O6
- Molecular Weight:289.29
IUPAC Name: N5-((S)-1-((carboxymethyl)amino)-1-oxobutan-2-yl)-L-glutamine
InChIKey: JCMUOFQHZLPHQP-BQBZGAKWSA-N
SMILES: OC(CNC([C@H](CC)NC(CC[C@H](N)C(O)=O)=O)=O)=O
Biological Activity: Ophthalmic acid is a ubiquitous metabolite and glutathione modulator, with a Ki of 0.95 mM for glyoxalase I. Ophthalmic acid competitively inhibits glyoxalase I, glutathione S-transferase, glutaredoxin, glutamate-cysteine ligase, protein disulfide reductase (glutathione), as well as non-selective cation channels. Ophthalmic acid is applicable in diabetes-related research[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ophthalmic acid | 99.91% | Ophthalmic acid is a ubiquitous metabolite and glutathione modulator, with a Ki of 0.95 mM for glyoxalase I. Ophthalmic acid competitively inhibits glyoxalase I, glutathione S-transferase, glutaredoxin, glutamate-cysteine ligase, protein disulfide reductase (glutathione), as well as non-selective cation channels. Ophthalmic acid is applicable in diabetes-related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ophthalmic acid (Standard) | ≥98% | Ophthalmic acid (Standard) is the analytical standard of Ophthalmic acid. This product is intended for research and analytical applications. Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
