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Cat. No.: HY-126752R

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Ophthalmic acid (Standard)

Ophthalmic acid (Standard) is the analytical standard of Ophthalmic acid (HY-126752). This product is intended for research and analytical applications. Ophthalmic acid is a ubiquitous metabolite and glutathione modulator, with a K_i of 0.95 mM for glyoxalase I. Ophthalmic acid competitively inhibits glyoxalase I, glutathione S-transferase, glutaredoxin, glutamate-cysteine ligase, protein disulfide reductase (glutathione), as well as non-selective cation channels. Ophthalmic acid is applicable in diabetes-related research.

For research use only. We do not sell to patients.

CAS No.: 495-27-2
Formula: C₁₁H₁₉N₃O₆
Molecular Weight:289.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ophthalmic acid (Standard) Chemical Structure

CAS No.: 495-27-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-126752
Ophthalmic acid

Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 495-27-2
Molecular Weight 289.29
Formula C₁₁H₁₉N₃O₆
SMILES

OC(CNC([C@H](CC)NC(CC[C@H](N)C(O)=O)=O)=O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Schomakers BV, et al. Ophthalmic acid is a glutathione regulating tripeptide. FEBS J. 2024;291(15):3317-3330. [Content Brief]

[2]. CLIFFE EE, et al. The mechanism of the glyoxalase I reaction, and the effect of ophthalmic acid as an inhibitor. Biochem J. 1961 Jun;79(3):475-82.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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