152684-53-2
152684-53-2
Chemical Structure
TLK117
Synonym(s): TER117
- CAS No.: 152684-53-2
- Formula:C23H27N3O6S
- Molecular Weight:473.54
IUPAC Name: N5-((R)-3-(benzylthio)-1-(((R)-carboxy(phenyl)methyl)amino)-1-oxopropan-2-yl)-L-glutamine
InChIKey: ZPSKWMFLCHMEOY-CMKODMSKSA-N
SMILES: OC([C@@H](N)CCC(N[C@@H](CSCC1=CC=CC=C1)C(N[C@H](C2=CC=CC=C2)C(O)=O)=O)=O)=O
Biological Activity: TLK117, the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1–1 (GSTP1-1) with a Ki of 0.4 μM for GSTP. TLK117 also competitively inhibits glyoxalase I with a Ki of 0.56 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TLK117 | 99.86% | TLK117, the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1–1 (GSTP1-1) with a Ki of 0.4 μM for GSTP. TLK117 also competitively inhibits glyoxalase I with a Ki of 0.56 μM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-13634AEzatiostat -
Similarity Score 0.79
HY-13634Ezatiostat hydrochloride -
Similarity Score 0.69
HY-148207S-Benzylglutathione -
Similarity Score 0.63
HY-N8115S-(4-Hydroxybenzyl)glutathione -
Similarity Score 0.61
HY-148208S-(p-Nitrobenzyl)glutathione -
Similarity Score 0.60
HY-P4552Hippuryl-Phe-Arg-OH -
Similarity Score 0.60
HY-114688BITC-SG -
Similarity Score 0.59
HY-148217DB02307 -
Similarity Score 0.59
HY-P4597(H-Cys-Phe-OH)2 (disulfide bond) -
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