S-(p-Nitrobenzyl)glutathione
Based on 1 Customer Validation
S-(p-Nitrobenzyl)glutathione is a competitive glutathionase inhibitor. S-(p-Nitrobenzyl)glutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-(p-Nitrobenzyl)glutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 6803-19-6
- Formula: C17H22N4O8S
- Molecular Weight:442.44
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 6803-19-6
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Appearance Solid
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Molecular Weight 442.44
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Formula C17H22N4O8S
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSCC1=CC=C(C=C1)[N+]([O-])=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (113.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. I García-Sáez, et al. Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J Mol Biol. 1994 Apr 1;237(3):298-314. [Content Brief]
[2]. T Suga, et al. Studies on mercapturic acids. Participation of glutathionase in the conversion of glutathione derivatives to cysteine derivatives. J Biochem. 1966 Aug;60(2):133-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2602 mL | 11.3010 mL | 22.6019 mL | 56.5048 mL |
| 5 mM | 0.4520 mL | 2.2602 mL | 4.5204 mL | 11.3010 mL | |
| 10 mM | 0.2260 mL | 1.1301 mL | 2.2602 mL | 5.6505 mL | |
| 15 mM | 0.1507 mL | 0.7534 mL | 1.5068 mL | 3.7670 mL | |
| 20 mM | 0.1130 mL | 0.5650 mL | 1.1301 mL | 2.8252 mL | |
| 25 mM | 0.0904 mL | 0.4520 mL | 0.9041 mL | 2.2602 mL | |
| 30 mM | 0.0753 mL | 0.3767 mL | 0.7534 mL | 1.8835 mL | |
| 40 mM | 0.0565 mL | 0.2825 mL | 0.5650 mL | 1.4126 mL | |
| 50 mM | 0.0452 mL | 0.2260 mL | 0.4520 mL | 1.1301 mL | |
| 60 mM | 0.0377 mL | 0.1883 mL | 0.3767 mL | 0.9417 mL | |
| 80 mM | 0.0283 mL | 0.1413 mL | 0.2825 mL | 0.7063 mL | |
| 100 mM | 0.0226 mL | 0.1130 mL | 0.2260 mL | 0.5650 mL |
S-(p-Nitrobenzyl)glutathione Related Classifications
HY-148208 Related Classifications
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